|Home About Us Hormones Conditions Stories Contact Us|
Pro: Latin : as in anticipation of an occurrence
Progesterone and Oestrogen are principally made in the ovaries of menstruating women, smaller amounts are made in the adrenal glands of both sexes and in the testes for males. Progesterone is dominant during pregnancy and otherwise regulates the menstrual cycle. It also acts as a calming hormone and helps to mediate inflammation.
Progesterone is manufactured by the corpus luteum, the 'yellow body' or empty egg follicle, after ovulation and tapering off just before the period if pregnancy does not occur. Its main job is to prepare the uterus for a fertilized egg while closing the cervix. One of Progesterone's roles is to prepare the uterus for a fertilized egg while closing the cervix. Progesterone production can reach 40mg daily in the second half of a regular menstrual cycle, skyrocketing to over 500mg daily in the last trimester of pregnancy.
The pivotal position of Progesterone in the hormone corticoid cascade is clear. It is the "Grandmother" of all hormones, leading in one direction to the corticosteroids and the other to the sex hormones, Testosterone and Oestrogens (E1, E2, E3).
There is overwhelming evidence that in our present environment, where most of us are subjected to a constant daily barrage of Phyto and Xeno-Oestrogens, many women by definition are exclusively Oestrogen dominant. It is this increasing imbalance between Oestrogens and Progesterone in menstruating women and the total lack of Progesterone in menopausal women; to balance the world we live in, which leads to the myriad of symptoms commonly suffered
A list of the principal functions of Progesterone include:
A list of conditions caused by Progesterone deficiency include:
Symptoms of Progesterone deficiency include:
Wild Yam is not Progesterone.
Many Physicians mistakenly believe that a Progestin (Synthetic drugs such as Provera) is the same as Progesterone and thus believe that Progesterone shares the same adverse side effects when in fact Progesterone has no known side effects. Below is a diagram of Progesterone and Provera, they started from the same molecule but subtle variations in a molecule cause changes in the original molecular functions, producing very different effects.
Natural Progesterone differs significantly in its action from its synthetic counterpart.
Molecules work like a key and lock combination. The right key (hormonal molecule) fits the right lock (Hormonal receptor) exactly and effects the appropriate action. With the synthetic Progestins while they fit the lock and occupy the receptors they cannot open the door to correct hormonal functioning and we experience the above adverse side effects.
Ref: Lee John: What your Doctor may not tell you about Menopause/Peri-menopause
Northrup Christiane: Women's Bodies, Women's Wisdom
Rees Uzzi: Natural Hormones
Cabot Sandra: Don't let Your Hormones Ruin Your Life.
Ahlgrimm, Marian & Kells, John L: The HRT Solution